Dietary supplements That Can Be Lethal When Mixed With Prescription Medicine

Dietary supplements That Can Be Lethal When Mixed With Prescription Medicine

On a regular basis dietary supplements, comparable to calcium, vitamin Ok, and potassium, can flip lethal when mixed with prescription drugs.

Vitamin D supplements

In the event you do not suppose you are getting sufficient vitamin D, you might wish to attempt dietary supplements.

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Nutritional vitamins are important for sustaining optimum physique features, from regulating heartbeats to therapeutic wounds.

Usually, folks can get a lot of the nutritional vitamins they want from consuming a well-balanced food regimen, however docs may recommend or prescribe dietary supplements in severely poor sufferers. The Facilities for Illness Management and Prevention has discovered that People are notably poor in vitamin B6, iron, vitamin D, and vitamin C.

Although gross sales for dietary supplements, together with nutritional vitamins, have skyrocketed in the course of the pandemic, taking these dietary supplements along side some prescription drugs can result in harmful well being outcomes.

Robert Alesiani, the chief pharmacotherapy officer at Tabula Rasa Healthcare, spoke with Insider concerning the on a regular basis nutritional vitamins that might flip deadly when mixed with sure prescription drugs.

“It is at all times good to have your physician or a pharmacist know the dietary supplements you take along side your prescription drugs,” Alesiani stated.

Combining St. John’s wort with HIV or posttransplant drugs may very well be deadly.

St. John's Wort supplement bottle sitting on pharmacy shelf

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St. John’s Wort is an natural treatment routinely prescribed for melancholy in Europe. Some managed research have discovered that St. John’s wort improves signs of melancholy in sufferers with gentle to average types of the sickness.

Alesiani stated the herb can set off the manufacturing of enzymes and proteins — discovered within the intestine, liver, and intestines — that expedite the pace wherein medication are absorbed by the physique. The speedy absorption can cut back the efficacy of medicines, because the physique excretes the medication too shortly earlier than they can be utilized. 

Alesiani added that St. John’s wort might trigger hurt by decreasing the efficacy of antiviral medication referred to as protease inhibitors, which block the replication of HIV cells within the physique.

Moreover, combining some antidepressants with St. John’s wort might additionally enhance the chance of serotonin toxicity, which might result in diarrhea, fever, seizures, and generally loss of life, Mayo Clinic stated.

Calcium, aluminum, and iron dietary supplements carry a optimistic cost that blocks the absorption of antibiotics.

A staged photo showing pills spilling out of an orange bottle.

A staged picture exhibiting capsules spilling out of an orange bottle.

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Calcium, aluminum, and iron dietary supplements all carry a optimistic cost (referred to as a “cation”) that bind to and will block some absorption of various antibiotics used to deal with quite a lot of illnesses, together with pneumonia, bladder infections, and the plague. 

“If a affected person’s taking antibiotics for an an infection, however they’re taking it along side calcium dietary supplements, it will probably block the absorption of these antibiotics, they usually might not get the sufficient ranges that they should handle that an infection,” Alesiani stated.

Antibiotics that grow to be much less efficient when mixed with these dietary supplements embody:

  • Ciprofloxacin, a medication that belongs to the fluoroquinolones class of antibiotics. It’s used to deal with bacterial infections in many alternative elements of the physique.
  • Ofloxacin, a medication that belongs to the fluoroquinolones class of antibiotics. Ofloxacin can deal with pneumonia, bladder infections, and prostate infections.
  • Demeclocycline, a medication that belongs to the tetracyclines class of antibiotics. Demeclocycline can deal with respiratory tract infections, pores and skin and eye infections, and infections unfold by ticks, lice, and mites.
  • Omadacycline, a medication that belongs to the tetracyclines class of antibiotics. Omadacycline can be utilized to deal with bacterial pneumonia and acute bacterial pores and skin and pores and skin construction infections.

Potassium dietary supplements mixed with coronary heart medication can result in a harmful enhance in blood stress.


Bananas include numerous potassium, which features as an electrolyte and nutrient.

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Potassium helps the physique regulate heartbeat, decrease blood stress, and aids in muscle and nerve functioning. An excessive amount of potassium can result in dangerous modifications in coronary heart rhythm and compromise kidney operate, Insider beforehand reported.

Alesiani stated potassium dietary supplements used along side drugs to deal with coronary heart issues or hypertension might trigger blood ranges to extend to harmful ranges. These drugs embody ACE inhibitors and angiotensin receptor blockers — which calm down the veins and arteries to decrease blood stress — aldosterone antagonists, and different potassium-sparing diuretics, which deal with hypertension by making you pee out extra salt to make it simpler to your coronary heart to pump blood. 

Vitamin Ok can cut back or improve the efficacy of lifesaving remedy that decreases blood clots.

vitamin k supplement pills and bottle

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Vitamin Ok is used for quite a lot of features, comparable to sustaining bone energy and defending towards coronary heart illness, and it is particularly vital in wound-healing. The vitamin turns blood from a liquid to a gel-like consistency that then varieties a scab, stopping the physique from bleeding to loss of life. 

Individuals who have had a coronary heart assault or fashioned a harmful blood clot within the lungs or veins are prescribed warfarin, a blood-thinning remedy that hinders clotting. Taking vitamin Ok dietary supplements with warfarin would both cut back or improve the efficacy of this drug, Alesiani stated, rising the chance of harmful clotting or bleeding.

“As a result of nutritional vitamins and different drugs can be found over-the-counter would not essentially imply that they are thought-about secure in all circumstances,” Alesiani stated.